Same Material procured with different vendors

Hi,      

The requirement is Material A having two size..10 and 30
ml....if I need Material A of 10 ml ---> I will procure from Vendor A...If
the requirement is for Material A of 30 ml --> I will procure from Vendor B.

The vendor is determined based on Size (10 or 30 ml)

In PR/PO, it should be determined based on Size.

Is it possible to acheive this scenario with Variant config or other means?

Thanks

Vasan